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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
38.79
Human Site:
Y435
Identified Species:
60.95
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
Y435
I
G
L
H
V
T
E
Y
E
D
N
L
K
N
S
Chimpanzee
Pan troglodytes
XP_517508
617
68419
Y435
I
G
L
H
V
T
E
Y
E
D
N
L
K
N
S
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
Y435
I
G
L
H
V
T
E
Y
E
D
N
L
K
N
S
Dog
Lupus familis
XP_853781
600
66768
Y418
I
G
L
H
V
T
E
Y
E
D
N
L
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
Y434
T
G
L
H
V
T
E
Y
E
D
N
L
K
Q
S
Rat
Rattus norvegicus
Q6UPE1
616
68180
Y434
A
G
L
H
V
T
E
Y
E
D
N
L
K
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
Y487
L
G
L
H
V
P
E
Y
E
E
N
L
K
N
S
Chicken
Gallus gallus
NP_001026705
477
53116
G307
P
L
D
R
H
T
Y
G
G
S
F
L
Y
H
L
Frog
Xenopus laevis
NP_001087869
616
68418
Y434
Q
G
L
D
V
P
E
Y
E
E
Q
L
K
K
S
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
Y435
T
G
L
Y
I
P
E
Y
E
E
A
L
K
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
G422
T
A
G
V
E
P
T
G
Y
A
E
K
I
K
D
Honey Bee
Apis mellifera
XP_624722
606
67014
T424
T
K
G
L
E
P
K
T
Y
T
E
K
I
Q
N
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
Y414
Q
T
I
D
P
A
T
Y
D
K
N
I
R
D
T
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
Y431
A
G
I
N
V
T
E
Y
E
D
R
L
K
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
A432
E
D
E
D
A
K
M
A
M
F
D
K
E
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
13.3
60
53.3
N.A.
0
0
13.3
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
93.3
20
66.6
73.3
N.A.
0
13.3
53.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
7
7
0
7
0
7
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
20
0
0
0
0
7
47
7
0
0
7
7
% D
% Glu:
7
0
7
0
14
0
67
0
67
20
14
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% F
% Gly:
0
67
14
0
0
0
0
14
7
0
0
0
0
0
0
% G
% His:
0
0
0
47
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
27
0
14
0
7
0
0
0
0
0
0
7
14
0
0
% I
% Lys:
0
7
0
0
0
7
7
0
0
7
0
20
67
27
0
% K
% Leu:
7
7
60
7
0
0
0
0
0
0
0
74
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
54
0
0
27
7
% N
% Pro:
7
0
0
0
7
34
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
0
0
0
0
0
7
0
0
20
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
67
% S
% Thr:
27
7
0
0
0
54
14
7
0
7
0
0
0
0
14
% T
% Val:
0
0
0
7
60
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
74
14
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _